Home> THYROID PROFILE
A Thyroid Profile Test is performed to accurately gauge the function of the thyroid gland, which plays a crucial role in regulating metabolism and other bodily functions such as heart rate, digestion, and body temperature.
A Thyroid Profile Test assesses levels of thyroid hormones (TSH, T4, and T3) to diagnose conditions like hypothyroidism, hyperthyroidism, and to monitor treatment effectiveness in thyroid disorders.
Autoimmune conditions affecting the thyroid gland, such as Hashimoto's thyroiditis and Graves' disease, can often be detected using a Thyroid Profile Test since the antibodies associated with autoimmune thyroid disorder are also assessed using a thyroid profile test.
A Thyroid Profile test assesses several key parameters related to thyroid function:
- TSH (Thyroid-Stimulating Hormone): As the name suggests, the TSH, synthesized by the anterior pituitary gland, stimulates the thyroid gland to produce T3 and T4. . TSH production is controlled by the hypothalamus through Thyrotropin-Releasing Hormone (TRH). TSH levels help determine if the thyroid gland is functioning properly. Elevated TSH levels indicate hypothyroidism (underactive thyroid), while low levels may suggest hyperthyroidism (overactive thyroid).
- T4 (Thyroxine): T4 is the main hormone produced by the thyroid gland and is converted into T3. It plays a crucial role in regulating metabolism, growth, and body temperature. High T4 levels may indicate hyperthyroidism, whereas low levels can suggest hypothyroidism. Abnormal levels of T4 can indicate thyroid disorders, affecting energy levels, weight, and overall health.
- T3 (Triiodothyronine): T3 is the active form of thyroid hormone. It influences metabolism, heart rate, and digestive function. T3 levels are crucial for cellular energy production and overall metabolic balance. Changes in T3 levels can impact energy levels, mood, and body temperature regulation
Together, TSH, T4, and T3 play interconnected roles in maintaining overall metabolic balance, energy production, and regulating numerous bodily functions. Monitoring these hormones helps diagnose and manage thyroid disorders effectively, ensuring optimal health and well-being.
- Free T4 (Free Thyroxine): 99% of T4 is bound to proteins (mainly thyroxine-binding globulin) . Only about 1% is free (unbound) and biologically active. Free T4 represents the amount of T4 that is not bound to proteins and is available for use by the body's cells. This helps assess thyroid function more accurately than total T4 levels, reflecting hormone availability.
- Free T3 (Free Triiodothyronine): Free T3 measures the amount of active T3 hormone available for cellular functions. This value is useful in diagnosing hyperthyroidism or monitoring treatment effectiveness in thyroid disorders.
- Thyroid Antibodies (TPOAb and TgAb): These antibodies are markers for autoimmune thyroid disorders like Hashimoto's thyroiditis (TPOAb) and Graves' disease (TgAb). Presence of antibodies indicates autoimmune thyroid disease, influencing treatment and management strategies.
A comprehensive Thyroid Profile test evaluates these parameters to diagnose thyroid disorders accurately, guiding appropriate treatment and management plans tailored to individual health needs.
Parathyroid hormone (PTH) is not typically measured as part of a standard thyroid profile test. PTH testing specifically evaluates parathyroid gland function and calcium regulation in the body. Separate tests may be required to assess PTH or Parathyroid Hormone levels.
Parathyroid hormone or PTH regulates the calcium and phosphate levels in the bloodstream. It is also crucial for bone health and neuromuscular function. PTH Testing is essential when diagnosing and managing disorders like hyperparathyroidism or hypoparathyroidism, which affect calcium balance.
Doctors order a Thyroid Profile Test to comprehensively assess thyroid function and diagnose various thyroid disorders. Here's why:
- Apart from providing a comprehensive picture of thyroid health and function, it helps diagnose hypothyroidism (underactive thyroid) or hyperthyroidism (overactive thyroid) based on hormone levels.
- Thyroid profile tests assess the effectiveness of thyroid medications and treatment plans
- Thyroid tests can aid in the diagnosis of autoimmune thyroid diseases like Hashimoto's thyroiditis and Graves' disease through antibody testing.
- Thyroid tests can also be used for routine health checks, especially in individuals with symptoms like fatigue, weight changes, and mood swings.
- They are also part of preventive health checkups and pre-empt complications such as cardiovascular disease, infertility, and osteoporosis.
Before undergoing a Thyroid Profile Test, consider these preparations and precautions:
- Schedule the test early in the morning for accurate TSH levels, which vary throughout the day.
- Some physicians may recommend fasting overnight before the test, especially if testing for TSH or thyroid antibodies.
- If you take thyroid medications, maintain your usual dosage schedule leading up to the test unless advised otherwise.
- Minimize iodine intake from supplements or iodized salt a few days before the test, as it can affect thyroid function tests.
- Notify your doctor of any medications you are currently on as some of them may alter the Thyroid profile test results.
Following these precautions helps ensure accurate and reliable results from your Thyroid Profile Test, guiding appropriate diagnosis and treatment decisions.
A Thyroid Profile Test is recommended for individuals who exhibit symptoms of thyroid dysfunction or those with risk factors such as:
- Those with symptoms like Fatigue, unintentional or unexplained weight changes, hair loss, mood swings, and irregular menstrual cycles.
- Those with symptoms like Fatigue, unintentional or unexplained weight changes, hair loss, mood swings, and irregular menstrual cycles.
- Those with a familial history of thyroid disorders
- People with autoimmune conditions like type 1 diabetes or rheumatoid arthritis
- Pregnant or breastfeeding women
- Older adults
- Those who have received radiation treatment to the head or neck
- Individuals with a history of thyroid disorders
Consult your physician to determine if a Thyroid Profile Test is appropriate based on your individual health history and symptoms.
Here’s a simplified explanation of how the thyroid profile test works:
Here’s a simplified explanation of how the thyroid profile test works: The obtained blood sample is sent to a laboratory where it undergoes analysis using specialized techniques such as:
- Immunoassays: Immunoassay techniques are commonly used to measure TSH, T4, and T3 levels. These tests rely on antibodies that specifically bind to each hormone. When the antibodies bind to the hormone in the blood sample, a detectable signal is produced, indicating the hormone concentration.
- LC-MS/MS (Liquid Chromatography Tandem Mass Spectrometry): In some cases, especially for more accurate measurement or when distinguishing between different forms of thyroid hormones (such as T4 and T3), LC-MS/MS may be used. This method separates and quantifies the hormones based on their mass and charge, providing precise measurements.
Once the hormone levels are measured, they are compared against established reference ranges. Abnormalities in TSH, T4, or T3 levels can indicate thyroid disorders such as hypothyroidism (low thyroid function) or hyperthyroidism (excess thyroid function).
Based on the results, physicians can diagnose thyroid conditions and recommend appropriate treatment or further testing if necessary.
The Thyroid Profile Test is generally quick, painless, safe and well tolerated. However, there are minimal risks associated with the thyroid profile test. The complications and risks of Thyroid tests are as follows:
- Temporary tenderness or bruising in the vicinity where blood was taken, usually easing soon after the test.
- Dizziness or fainting can occur in some individuals following the blood draw, especially if they have a fear of needles or are prone to anxiety.
- While rare, there is a slight risk of infection at the needle insertion point, which is mitigated by thorough sterilization measures
- In rare cases, excessive bleeding can occur, particularly in individuals with bleeding disorders or who are taking blood-thinning medications.
Normal Range of Thyroid Stimulating Hormone (TSH) : Typically between 0.55 and 4.78 µIU/mL.
Normal Range of T4 (Thyroxine): Approximately between 3.2 and 12.6 µg/dL.
Normal Range of T3 (Triiodothyronine): Between 0.60 and 1.81 ng/mL.
Biological Reference Intervals may vary based on gender and Age.
Elevated TSH levels and low levels of T3 and T4 may be indicative of hypothyroidism or an underactive thyroid. On the other hand, high levels of T3 and T4 with reduced TSH levels could suggest hyperthyroidism or an overactive thyroid.
Presence of Thyroid Antibodies (TPOAb and TgAb) Indicates autoimmune thyroid disorders like Hashimoto's or Graves' disease.or that there is an autoimmune cause for thyroid dysfunction.
Results are interpreted based on individual ranges provided by the laboratory. Abnormalities may require further testing or treatment adjustments to manage thyroid conditions effectively.
Choose from over 5000 diagnostic tests, from routine checkups to advanced radiology tests such as PET CT and 3T MRI. Book appointments instantly, get samples collected at home, and access your medical history - all on your phone using the user-friendly Vijaya Diagnostics app.
Choose Vijaya Diagnostics - because your health deserves nothing less!
Ans) Thyroid tests can be done anytime, though some doctors might prefer them in the morning for consistency.
Ans) Thyroid Profile test results typically arrive on the same day, but it may vary depending on the lab.
Ans) Frequency of Thyroid testing may vary significantly based on individual medical conditions. Thyroid tests are also generally part of preventive health checkups. Seek personalized advice from your doctor. For abnormalities in the initial diagnosis and treatment adjustments, it's recommended to test every 6 to 8 weeks until hormone levels stabilize.
Ans) A Thyroid Profile typically includes tests to gauge TSH (Thyroid Stimulating Hormone), the primary thyroid hormone, T4 (Thyroxine), and T3 (Triiodothyronine) levels.
Ans) Fasting may not always be necessary for a Thyroid Profile test but it is strongly recommended to check with your doctor for personalized recommendations.
Ans) High T4 levels may indicate hyperthyroidism, necessitating further evaluation.
Ans) The cost of a Thyroid Profile Test may significantly vary depending on factors like the diagnostic center or hospital where you get the Thyroid Profile Test and the location of the diagnostic center or hospital. The Thyroid Profile Test price at Vijaya Diagnostic typically ranges from just INR 500 to INR 700. Plus, with app-only discounts and cashback, taking care of your health has never been easier or more rewarding.
Ans) A Thyroid Profile Test can detect thyroid disorders such as hypothyroidism, Hashimoto's thyroiditis (TPOAb), Graves' disease (TgAb), and hyperthyroidism.
Ans) If you are searching for a reliable and affordable diagnostic center to get a thyroid test near you, then Vijaya Diagnostics is your ideal choice. With over 140+ state-of-the-art labs across 20+ cities, you can easily locate a Vijaya Diagnostic center nearby!
What’s more? We offer thyroid tests, preventive health checkups, and other blood tests right at your doorstep through our home sample collection service. Book a convenient time slot using our app and enjoy exclusive discounts, cashbacks, and more on the Vijaya Diagnostic app! Alternatively, you can call us at 040 - 2100 0000 or select your preferred test directly from the Vijaya Diagnostics website.