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Patient Preparation: No special preparation is required
SGOT is typically used as a Liver Function Test; i.e. to detect liver damage. SGOT is almost always ordered along with SGPT. Symptoms of a liver disorder usually include weakness, fatigue, loss of appetite, abdominal swelling, pain, jaundice etc.
SGOT test is also ordered for people who are at high risk of liver damage. Often liver damage does not show symptoms for long, and go unnoticed. In such situations, regular checking for SGOT and SGPT can detect the abnormalities early, and helps in effective management of the disorder. This is critical especially in patients at high risk of liver disorders, such as people with obesity, diabetes, heavy drinkers, or those taking certain medications causing harm to the liver in the long-term.
Your doctor may recommend this test for you if you show signs of liver damage. They include:
Loss of appetite
SGOT is also called as aspartate aminotransferase (AST) is an enzyme (protein) normally found in liver and heart. High levels of SGOT are seen in the blood when the liver cells are damaged (ex-viral hepatitis) or when there is exertion on the heart muscles (ex. heart attack), when SGOT leaks into the blood.
SGOT is an important enzyme used to test the liver function.
Very high levels of SGOT (more than 10 times normal) are indicative of liver disorders such as acute hepatitis. Levels of SGOT is over 1000 times normal in an event of exposure to drugs or other substances that are toxic to the liver as well as in conditions that can cause decreased blood flow (ischemia) to the liver.
With chronic hepatitis, SGOT levels may not go as high and remain at levels which are roughly 4 times the normal range, and are more likely to remain normal than SGPT levels.
In most types of liver disease, the SGOT level is higher than SGPT and the ratio will be less than 1. However in certain liver disorders like alcoholic hepatitis and cirrhosis, the ratio can go higher.
Sample: 2 mL of Serum
Methodology: IFCC without P5P